The efficacy of an association of palmitoylethanolamide and alpha-lipoic acid in patients with chronic prostatitis/chronic pelvic pain syndrome: A randomized clinical trial
Randomised controlled trialHumansWith alpha-lipoic acid
This study tested palmitoylethanolamide together with alpha-lipoic acid. Its results cannot be assigned to palmitoylethanolamide alone. More combination studies.
- Design
- Randomised controlled trial
- Subjects
- 44 men with chronic prostatitis or chronic pelvic pain syndrome
- Dose used in the study
- 300 mg of palmitoylethanolamide with 300 mg of alpha-lipoic acid (Peanase), compared with 320 mg of saw palmetto
- Duration
- 12 weeks
- What was measured
- The NIH chronic prostatitis symptom index, a urinary symptom score and an erectile function score
What the authors reported
The authors reported that the combination improved the urinary symptom score and reduced the prostatitis symptom score more than saw palmetto. Erectile function scores did not change significantly. Neither treatment produced side effects.
Limits of this study
Single-blind, so the researchers knew the allocation. The comparison was with saw palmetto, not placebo, and saw palmetto has no established effect in this condition. 44 patients and 12 weeks. The entry was checked against the abstract only. Funding was not listed.
Source
Entry checked against the abstract and citation held by Crossref, the DOI registry on 2026-09-21. The dose shown is the dose the researchers used. It is not a recommendation. How to read this page.