The Enteric Glia and Its Modulation by the Endocannabinoid System, a New Target for Cannabinoid-Based Nutraceuticals?
ReviewHumansOther animals
- Design
- Review
- Subjects
- Not applicable; a narrative review
- Dose used in the study
- Not stated in the abstract
- Duration
- Not stated in the abstract
- What was measured
- Whether the endocannabinoid system, including palmitoylethanolamide and OEA, could be a target for modulating enteric glial cells that support gut barrier integrity, neuroprotection, motility and sensation.
What the authors reported
Enteric glia are immune-competent cells supporting gut barrier integrity, neuroprotection, motility and sensation, and the authors summarise how endocannabinoid receptors, enzymes and ligands including palmitoylethanolamide might modulate them. No PEA-specific data are given in the abstract.
Limits of this study
A narrative review, not new data. The authors declare no conflict of interest.
Source
PubMed 36235308 · doi:10.3390/molecules27196773
Entry checked against the abstract on PubMed on 2026-09-22. The dose shown is the dose the researchers used. It is not a recommendation. How to read this page.