Therapeutic Potential of Diacerein in Management of Pain
ReviewHumansOther animals
- Design
- Review
- Subjects
- Not applicable; a narrative review
- Dose used in the study
- Not stated in the abstract
- Duration
- Not stated in the abstract
- What was measured
- How diacerein and rhein act on pain: their effects on mediators involved in neuropathic, inflammatory and nociceptive pain, including TRPV1, substance P, cytokines, histamine, palmitoylethanolamide, NF-kB and prostaglandins
What the authors reported
Diacerein and rhein appear to affect several pain mediators, including palmitoylethanolamide, though the authors say clinical trials and mechanism studies are still needed. No PEA-specific data are given in the abstract.
Limits of this study
A narrative review of another drug; PEA is mentioned only as a mediator. Funding and conflicts not stated in the abstract.
Source
PubMed 36281831 · doi:10.2174/2589977514666220428124623
Entry checked against the abstract on PubMed on 2026-09-22. The dose shown is the dose the researchers used. It is not a recommendation. How to read this page.