RETRACTED: Peritore et al. Ultramicronized Palmitoylethanolamide and Paracetamol, a New Association to Relieve Hyperalgesia and Pain in a Sciatic Nerve Injury Model in Rat. Int. J. Mol. Sci. 2020, 21, 3509

Alessio Filippo Peritore, Rosalba Siracusa, Roberta Fusco, Enrico Gugliandolo, Ramona D'Amico, Marika Cordaro, Rosalia Crupi, Tiziana Genovese, Daniela Impellizzeri, Salvatore Cuzzocrea, Rosanna Di Paola. Int J Mol Sci. 2026 Apr 16;27(8):3545.

ReviewOther animalsWith paracetamol

This study tested palmitoylethanolamide together with paracetamol. Its results cannot be assigned to palmitoylethanolamide alone. More combination studies.

Design

Review

Subjects

Not stated in the abstract

Dose used in the study

Not stated in the abstract

Duration

Not stated in the abstract

What was measured

This entry records a retraction notice, not a study finding: what was retracted and why

What the authors reported

The journal retracted the article "Ultramicronised Palmitoylethanolamide and Paracetamol, a New Association to Relieve Hyperalgesia and Pain in a Sciatic Nerve Injury Model in Rat" by Peritore AF et al (PMID 32429243). The retraction notice gives no detailed reason in the text captured here.

Limits of this study

This is a retraction: the original 2020 rat-model findings on PEA plus paracetamol for sciatic nerve injury pain should no longer be relied on. No conflict or funding information is stated in the notice.

Source

PubMed 41989843 · doi:10.3390/ijms27083545

Entry checked against the PubMed record; the notice has no abstract on 2026-09-22. The dose shown is the dose the researchers used. It is not a recommendation. How to read this page.