palmitoylethanolamide.com.au
HomeResearchS 2021

Roles of Endocannabinoids and Endocannabinoid-Like Molecules in Energy Homeostasis and Metabolic Regulation: A Nutritional Perspective

S M Khaledur Rahman, Toru Uyama, Zahir Hussain, Natsuo Ueda. Annu Rev Nutr. 2021 Oct 11:41:177-202.

ReviewHumansOther animals

Design
Review
Subjects
Not stated in the abstract
Dose used in the study
Not stated in the abstract
Duration
Not stated in the abstract
What was measured
How endocannabinoids and endocannabinoid-like molecules, including palmitoylethanolamide, oleoylethanolamide and 2-oleoylglycerol, act in energy balance and metabolic regulation, with a nutritional perspective on their structure, metabolism and biological activities

What the authors reported

Endocannabinoids are described as stimulating feeding and lipid and glucose anabolism, while oleoylethanolamide suppresses appetite. Palmitoylethanolamide is grouped with the endocannabinoid-like molecules that act on other receptors rather than cannabinoid receptors. No PEA-specific results are given.

Limits of this study

A narrative review with no numbers. Funding and conflicts not stated in the abstract.

Source

PubMed 34115519 · doi:10.1146/annurev-nutr-043020-090216

Entry checked against the abstract on PubMed on 2026-09-22. The dose shown is the dose the researchers used. It is not a recommendation. How to read this page.