Successful and Unsuccessful Brain Aging in Pets: Pathophysiological Mechanisms behind Clinical Signs and Potential Benefits from Palmitoylethanolamide Nutritional Intervention
ReviewDogsCats
- Design
- Review
- Subjects
- Narrative review
- Dose used in the study
- Not applicable
- Duration
- Not applicable
- What was measured
- Mechanisms of cognitive dysfunction syndrome in old dogs and cats, and animal-model evidence for ultramicronised palmitoylethanolamide
What the authors reported
Ultramicronised palmitoylethanolamide has been tested repeatedly in animal models of age-related neurodegeneration with encouraging results, the authors say, and they suggest it may support brain ageing in pets.
Limits of this study
The evidence cited is from laboratory models, not from trials in old dogs or cats. No such trial is in this database. Authors declare no conflicts; the first author has published with the Epitech-linked Rome group.
Source
PubMed 34573549 · doi:10.3390/ani11092584
Entry checked against the abstract on PubMed on 2026-09-22. The dose shown is the dose the researchers used. It is not a recommendation. How to read this page.