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Palmitoylethanolamide/Luteolin as Adjuvant Therapy to Improve an Unusual Case of Camptocormia in a Patient with Parkinson's Disease: A Case Report

Stefania Brotini. Innov Clin Neurosci. 2021 Oct-Dec;18(10-12):12-14.

Case seriesHumansWith luteolin (co-ultramicronised with palmitoylethanolamide, um-PEALut)

This study tested palmitoylethanolamide together with luteolin (co-ultramicronised with palmitoylethanolamide, um-PEALut). Its results cannot be assigned to palmitoylethanolamide alone. More combination studies.

Design
Case series
Subjects
One patient with Parkinson's disease and camptocormia
Dose used in the study
Um-PEALut (co-ultramicronised palmitoylethanolamide and luteolin) added to carbidopa/levodopa therapy
Duration
4 months
What was measured
Dyskinesia and camptocormia severity during 'on' and 'off' Parkinson's disease states after adding um-PEALut to dopaminergic therapy

What the authors reported

Adding um-PEALut to carbidopa/levodopa improved dyskinesia and reduced camptocormia. After 4 months of treatment the patient had complete resolution of leg and trunk dyskinesia and a marked reduction in camptocormia during 'off' states.

Limits of this study

A single case report with no control group; it cannot show effect beyond this one patient. The author declares no conflicts of interest relevant to the article.

Source

PubMed 35096476

Entry checked against the abstract on PubMed on 2026-09-22. The dose shown is the dose the researchers used. It is not a recommendation. How to read this page.