palmitoylethanolamide.com.au
HomeResearchChirchiglia 2018

Nonsurgical lumbar radiculopathies treated with ultramicronized palmitoylethanolamide (umPEA): A series of 100 cases

Chirchiglia D, Chirchiglia P, Signorelli F. Neurol Neurochir Pol. 2018;52(1):44-47.

Case seriesHumans

Design
Case series
Subjects
100 patients (73 men, 27 women, aged 45 to 75) with chronic low back pain from degenerative lumbar disease without surgical indication, reviewed retrospectively
Dose used in the study
Ultramicronised PEA together with paracetamol and codeine; PEA dose not given in the abstract or preview
Duration
Two treatment cycles with checks at one and two months
What was measured
Pain on a visual analogue scale

What the authors reported

After one month, mean VAS fell by 1.9, 2.7 and 2.3 points in the mild, moderate and severe baseline groups (p < 0.0001), with further improvement after the second cycle. About 80 percent responded. No adverse effects.

Limits of this study

Retrospective case series with no control group. PEA was given with paracetamol and codeine, so the PEA contribution cannot be separated. PEA dose not stated in the text available.

Source

PubMed 29157720 · doi:10.1016/j.pjnns.2017.11.002

Entry checked against the abstract and preview, supplied by Devlin. PEA dose not in the text available on 2026-09-21. The dose shown is the dose the researchers used. It is not a recommendation. How to read this page.