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Optimization of Fermentation Conditions and Metabolite Profiling of Grape Juice Fermented with Lactic Acid Bacteria for Improved Flavor and Bioactivity

Dilinu Kuerban, Jing Lu, Zekun Huangfu, Liang Wang, Yanan Qin, Minwei Zhang. Foods. 2023 Jun 18;12(12):2407.

Laboratory studyOther animals

Design
Laboratory study
Subjects
Grape juice fermented with four lactic acid bacteria strains; no animals or people
Dose used in the study
Not applicable; palmitoylethanolamide was detected as a metabolite in the juice
Duration
Fermentation 24 hours at 41.2 degrees C; storage 45 days at 4 degrees C
What was measured
Fermentation conditions, polyphenol retention, 251 metabolites and 85 volatile compounds in fermented grape juice.

What the authors reported

The study found:

  • Total polyphenols were 92.65% retained at the end of fermentation and 50% after 45 days of storage.
  • Among the metabolites, palmitoylethanolamide and tetraacetylethylenediamine increased with fermentation while linamarin decreased, which the authors link to taste.
  • Esters, aldehydes and alcohols were the main volatiles.

Limits of this study

A food chemistry study; it says nothing about PEA's effect in people or animals, and the PEA amount is not given in the abstract. The authors declare no conflict of interest.

Source

PubMed 37372618 · doi:10.3390/foods12122407

Entry checked against the abstract on PubMed on 2026-09-22. The dose shown is the dose the researchers used. It is not a recommendation. How to read this page.