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HomeResearchPetrosino 2017

The pharmacology of palmitoylethanolamide and first data on the therapeutic efficacy of some of its new formulations

Petrosino S, Di Marzo V. British Journal of Pharmacology, 2017; 174(11):1349-1365.

ReviewHumansOther animals

Design
Review
What was measured
An overview of the pharmacology, efficacy and safety of palmitoylethanolamide in neurodegenerative disorders, pain and inflammatory disease, including micronised and ultramicronised forms and combinations with luteolin and polydatin

What the authors reported

The authors describe palmitoylethanolamide as a compound made in many plant and animal foods and in mammalian tissues, with protective, anti-inflammatory and pain-related actions in laboratory work. They review the proposed mechanisms and the first data on smaller-particle formulations, alone and in combination.

Limits of this study

A narrative review. The entry was checked against the abstract only, which gives no numbers. For a more critical reading of the same literature, see Rankin 2020 and Gabrielsson 2016 in this database.

Source

doi:10.1111/bph.13580

Entry checked against the abstract and citation held by Crossref, the DOI registry on 2026-09-21. The dose shown is the dose the researchers used. It is not a recommendation. How to read this page.