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Could Palmitoylethanolamide Be an Effective Treatment for Long-COVID-19? Hypothesis and Insights in Potential Mechanisms of Action and Clinical Applications

Loredana Raciti, Francesca Antonia Arcadi, Rocco Salvatore Calabrò. Innov Clin Neurosci. 2022 Jan-Mar;19(1-3):19-25.

ReviewHumans

Design
Review
Subjects
Not applicable; a hypothesis and review article
Dose used in the study
Not applicable; a hypothesis and review article
Duration
Not applicable; a hypothesis and review article
What was measured
Whether palmitoylethanolamide could help treat long-COVID: proposed mechanisms and possible clinical applications

What the authors reported

Palmitoylethanolamide is put forward as a possible treatment for long-COVID, particularly fatigue and myalgia, reasoning from its proposed anti-inflammatory and cytokine-modulating properties and a hypothesised role for mitochondrial dysfunction in long-COVID. No new experimental or clinical data are given.

Limits of this study

A hypothesis and narrative review, not a study; it reports no new experimental or clinical results and cannot show effect in people. The authors declare no conflicts of interest relevant to the article.

Source

PubMed 35382075

Entry checked against the abstract on PubMed on 2026-09-22. The dose shown is the dose the researchers used. It is not a recommendation. How to read this page.