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Micronized / ultramicronized palmitoylethanolamide (PEA) as natural neuroprotector against COVID-19 inflammation

Luca Roncati, Beatrice Lusenti, Federica Pellati, Lorenzo Corsi. Prostaglandins Other Lipid Mediat. 2021 Jun:154:106540.

ReviewHumans

Design
Review
Subjects
A mini-review plus one 45-year-old woman with COVID-19
Dose used in the study
Micronised and ultramicronised palmitoylethanolamide; dose not stated in the abstract
Duration
Not stated in the abstract
What was measured
Why phospholipid intake and possible secondary antiphospholipid syndrome matter in COVID-19, illustrated with a single case report of PEA use

What the authors reported

One 45-year-old woman with COVID-19 was, in the authors' words, treated with success using micronised and ultramicronised PEA. The review also sets out PEA's anti-inflammatory and neuroprotective properties. No outcome measures, dose or timing are given in the abstract.

Limits of this study

A narrative review with a single uncontrolled case, no dose and no outcome data in the abstract; it cannot show that PEA affected COVID-19. The authors declare no competing interest.

Source

PubMed 33636368 · doi:10.1016/j.prostaglandins.2021.106540

Entry checked against the abstract on PubMed on 2026-09-22. The dose shown is the dose the researchers used. It is not a recommendation. How to read this page.