Novel Approach to the Treatment of Neuropathic Pain Using a Combination with Palmitoylethanolamide and Equisetum arvense L. in an In Vitro Study
Laboratory studyOther animalsWith Equisetum arvense L. (horsetail) extract
This study tested palmitoylethanolamide together with Equisetum arvense L. (horsetail) extract. Its results cannot be assigned to palmitoylethanolamide alone. More combination studies.
- Design
- Laboratory study
- Subjects
- A 3D intestinal barrier model and a 3D nerve tissue model with Schwann cell injury; cell sources not stated in the abstract
- Dose used in the study
- Not stated in the abstract
- Duration
- Not stated in the abstract
- What was measured
- Passage across a 3D intestinal barrier model and cytotoxicity; effects on nerve recovery and pain-related mechanisms in a 3D nerve tissue model after Schwann cell injury
What the authors reported
The combination crossed the intestinal barrier model without cytotoxicity, reached the nerve model, and modulated nerve recovery after Schwann cell injury. No numbers are given in the abstract.
Limits of this study
A cell-model study; it cannot show effect in people or animals treated in practice. No doses or numbers are given in the abstract. The senior author is a co-founder of noivita Srls; the authors otherwise declare no conflict.
Source
PubMed 36982577 · doi:10.3390/ijms24065503
Entry checked against the abstract on PubMed on 2026-09-22. The dose shown is the dose the researchers used. It is not a recommendation. How to read this page.