Manganese affects the growth and metabolism of Ganoderma lucidum based on LC-MS analysis
Laboratory studyOther animals
- Design
- Laboratory study
- Subjects
- Fruiting bodies of the fungus Ganoderma lucidum grown with or without 200 mg/kg manganese
- Dose used in the study
- Not applicable; palmitoylethanolamide was detected as a fungal metabolite
- Duration
- Not stated in the abstract
- What was measured
- Mycelial growth, yield, manganese peroxidase activity, polysaccharide, triterpenoid and manganese content, and metabolite profiles by LC-MS
What the authors reported
The study found:
- Manganese changed growth, yield, enzyme activity and composition.
- Sixteen metabolites differed, 5 down and 11 up.
- Chavicol and palmitoylethanolamide were among the most strongly up-regulated in manganese-treated samples.
- Glycerophospholipid metabolism was the most affected pathway.
Limits of this study
A mushroom metabolomics study; palmitoylethanolamide was one metabolite that rose with manganese. It says nothing about effects in people or animals. The authors declare no competing interests.
Source
PubMed 31106063 · doi:10.7717/peerj.6846
Entry checked against the abstract on PubMed on 2026-09-22. The dose shown is the dose the researchers used. It is not a recommendation. How to read this page.