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HomeResearchCostagliola 2014

Effect of Palmitoylethanolamide on Visual Field Damage Progression in Normal Tension Glaucoma Patients: Results of an Open-Label Six-Month Follow-Up

Costagliola C, Romano MR, dell'Omo R, Russo A, Mastropasqua R, Semeraro F. Journal of Medicinal Food, 2014; 17(9):949-954.

Controlled trialHumans

Design
Controlled trial
Subjects
32 patients with normal tension glaucoma, randomised to palmitoylethanolamide or no treatment
Dose used in the study
300 mg of ultramicronised palmitoylethanolamide twice a day
Duration
6 months
What was measured
Eye pressure, visual acuity and visual field indices

What the authors reported

The authors reported that eye pressure fell from 14.4 to 11.1 mmHg in the treated group (p < 0.01), and that two visual field indices improved compared with baseline. Visual acuity did not change in either group. No side effects were recorded.

Limits of this study

Open-label, with no placebo. The comparison group received nothing, so patients and examiners knew who was treated. 32 patients and 6 months. The entry was checked against the abstract only. Funding was not listed.

Source

doi:10.1089/jmf.2013.0165

Entry checked against the abstract and citation held by Crossref, the DOI registry on 2026-09-21. The dose shown is the dose the researchers used. It is not a recommendation. How to read this page.